1 1 carbonyldiimidazole cdi
1,1 Carbonyldiimidazole (CDI) is a versatile chemical reagent widely used in organic synthesis and pharmaceutical manufacturing. This white crystalline solid serves as an efficient coupling agent for the formation of amides, esters, and other carbonyl-containing compounds. Its molecular structure consists of two imidazole rings connected by a carbonyl group, making it highly reactive and selective in various chemical transformations. CDI functions by activating carboxylic acids through the formation of reactive intermediates, facilitating subsequent reactions with nucleophiles like amines or alcohols. The reagent's popularity stems from its ability to produce high yields under mild conditions while generating relatively benign byproducts. In pharmaceutical applications, CDI plays a crucial role in peptide synthesis and the production of active pharmaceutical ingredients. Its technological features include excellent stability when stored properly, consistent reaction outcomes, and compatibility with various solvents. The compound's applications extend beyond pharmaceuticals into polymer chemistry, where it aids in the synthesis of polyurethanes and other specialty materials.