inexpensive nncarbonyldiimidazole
N,N-Carbonyldiimidazole (CDI) is a versatile and cost-effective reagent widely used in organic synthesis and pharmaceutical manufacturing. This white crystalline compound serves as an efficient coupling agent for the formation of amides, esters, and other important chemical bonds. Its inexpensive nature makes it particularly attractive for large-scale industrial applications while maintaining high reaction yields. The compound works by activating carboxylic acids through the formation of reactive intermediates, enabling smooth coupling reactions under mild conditions. Its stability at room temperature and ease of handling make it a practical choice for both research laboratories and industrial settings. When compared to alternative coupling reagents, inexpensive CDI offers superior atom economy and generates imidazole as its only byproduct, which can be easily separated from reaction mixtures. The compound's versatility extends to its ability to form urethanes, ureas, and carbonates, making it an invaluable tool in diverse synthetic applications.